HIV and Covid-19

HIV and Covid-19

In the beginning of the Covid-19 pandemic, those of us that care for patients with HIV/AIDs were very concerned on how it would impact these patients. HIV is considered a risk factor for worse outcomes to Covid-19 because of the immunocompromised state it creates in those infected with HIV. Unfortunately, there are other risk factors associated with HIV that add other comorbidities that are also considered high risk for Covid-19. Patients with HIV are at an increased risk of cardiovascular disease. Patients with HIV have a two times greater chance of having a cardiovascular event or stroke compared to those without HIV. Mechanisms for this is still not well understood, but it appears to be due to metabolic derangements associated with HIV, regardless of viral suppression due to antiretroviral therapy.

In addition, patients with HIV also have abnormal accumulation for adipose tissue, both subcutaneously and in the viscera (internal organs). Again, the mechanisms for these phenomena are multifactorial and not completely understood. Regardless, these patients exist in a pro-inflammatory state which is chronic. In relation to Covid-19, we are now understanding the importance between the virus and underlying chronic inflammatory states. Covid-19 is known to cause an abnormal cytokine storm, or more like a cytokine explosion, in high-risk patients, which is analogous to gasoline on a fire.

Thankfully my HIV patients faired very well through the pandemic, with no hospitalizations or deaths. They are, for the most part, compliant with their therapies and were adherent to sheltering in place and masking.

Despite doing everything right, there were several patients that still contracted Covid-19. Amazingly, their symptoms were minimal. In one case, my patient had a two-day history of a low-grade fever, mild sore throat, and dry cough. One week after his symptoms, he was seen in the office and asked if that could be Covid. Blood work revealed he was positive Covid-19 IgA, IgM and IgG indicating a recent infection.

Another case was a young man in his late twenties who shares a house with his partner and two other men around the same age. He is the only one who is HIV positive and on antiretroviral therapy. Apparently Covid had struck the other three severely and he only had minimal symptoms and took care of the other three.

This has also been seen in general, that people with HIV did not have a more grievous outcome to Covid-19 if they were on antiretroviral therapy. It appears as if the antiretroviral therapy acted as a prophylaxis against the Covid-19 virus. It did not prevent patients with HIV from getting sick, but it appears as if the antiretrovirals, several which are known to have benefit against Covid-19 such as tenofovir and emtricitabine, diminished viral replication enough to prevent that cytokine explosion from occurring until the patient’s immune system could eliminate the virus.

This is not to suggest that those without HIV should be going on such medications for Covid-19 prophylaxis, but it does shed light on the fact that prophylaxis could be an important adjunct in combating Covid-19, especially considering all the breakthrough cases we are now seeing with the vaccines. There are many unknowns as we continue into this second year of the pandemic, we need more tools in the toolbox to fight it, not less.

By | 2021-10-01T16:24:57-04:00 August 10th, 2021|COVID, Infectious Disease|

About the Author:

I am a passionate blogger, author, speaker and 3X Board Certified MD in Infectious Disease, Internal & Sleep Medicine. I currently am an infectious disease physician in Atlanta, GA for Infectious Disease Consultants.


  1. shorten url link free October 27, 2021 at 8:52 pm - Reply

    Wow, wonderful blog layout! How long have you been blogging for? you made running a blog look easy. The overall look of your web site is magnificent, let alone the content material!!

  2. shortening to butter conversion November 2, 2021 at 5:45 am - Reply

    Wow, superb blog structure! How long have you ever been blogging for? you made running a blog glance easy. The entire look of your web site is wonderful, as smartly as the content material hitman

  3. Quantum Biofeedback November 3, 2021 at 8:57 pm - Reply

    I really appreciate this post. I have been looking all over for this! Thank goodness I found it on Bing. You’ve made my day! Thanks again! soyos

  4. QHHT November 8, 2021 at 8:21 am - Reply
  5. dunkinrunsonyou com November 8, 2021 at 7:50 pm - Reply

    I love visiting your wordpress blog. You are simply crafty and also create so thoroughly. Cheers with regard to working doggedly on this particular weblog.

  6. I adore seeing your wordpress blog. You are actually wise and write so adequately. Thanks with regards to striving on this wordpress blog.

  7. Tntdrama com/activate November 13, 2021 at 1:54 pm - Reply

    I am curious to find out what blog platform you have been utilizing? I’m having some small security issues with my latest website and I’d like to find something more risk-free. Do you have any suggestions?

  8. Woah! I’m really digging the template/theme of this site. It’s simple, yet effective. A lot of times it’s very hard to get that “perfect balance” between usability and appearance. I must say you’ve done a awesome job with this. Additionally, the blog loads extremely quick for me on Internet explorer. Superb Blog!

  9. getinkpreferred invitation number November 16, 2021 at 7:30 pm - Reply

    Excellent blog! Do you have any recommendations for aspiring writers? I’m hoping to start my own blog soon but I’m a little lost on everything. Would you suggest starting with a free platform like WordPress or go for a paid option? There are so many choices out there that I’m completely overwhelmed .. Any ideas? Thank you!

  10. vao 12bet No1 November 17, 2021 at 3:12 am - Reply

    Its like you read my mind! You seem to understand so much about this, like you wrote the e book in it or something. I believe that you just could do with some to force the message house a little bit, however other than that, that is fantastic blog. A great read. I’ll certainly be back.

  11. Www tntdrama com/activate November 18, 2021 at 6:48 pm - Reply

    Wonderful blog! Do you have any helpful hints for aspiring writers? I’m planning to start my own blog soon but I’m a little lost on everything. Would you advise starting with a free platform like WordPress or go for a paid option? There are so many options out there that I’m totally confused .. Any recommendations? Cheers!

  12. firestick November 18, 2021 at 10:05 pm - Reply

    Hello. magnificent job. I did not anticipate this. This is a impressive story. Thanks!

  13. Www aainflight com November 19, 2021 at 4:53 am - Reply

    I precisely desired to thank you so much yet again. I’m not certain what I could possibly have used without those solutions revealed by you over such subject. This has been a real hard issue in my opinion, but witnessing the very professional form you solved it forced me to jump for happiness. I am thankful for your work and then sincerely hope you realize what an amazing job you are accomplishing teaching other individuals using your web page. Most probably you have never met all of us.

  14. November 19, 2021 at 6:25 am - Reply

    I absolutely love your blog and find many of your post’s to be precisely what I’m looking for. can you offer guest writers to write content for you personally? I wouldn’t mind composing a post or elaborating on a lot of the subjects you write regarding here. Again, awesome website!

  15. read November 19, 2021 at 4:31 pm - Reply

    Hey there! I’ve been following your site for a long time now and finally got the bravery to go ahead and give you a shout out from Porter Tx! Just wanted to mention keep up the great job!

  16. November 19, 2021 at 8:01 pm - Reply

    Awesome blog! Is your theme custom made or did you download it from somewhere? A theme like yours with a few simple tweeks would really make my blog jump out. Please let me know where you got your design. Kudos

  17. yourvervecard mastercard November 20, 2021 at 2:51 am - Reply

    Magnificent goods from you, man. I have understand your stuff previous to and you are just too magnificent. I really like what you have acquired here, really like what you are saying and the way in which you say it. You make it enjoyable and you still take care of to keep it sensible. I cant wait to read far more from you. This is really a tremendous site.

  18. Tnt drama on roku November 20, 2021 at 5:17 am - Reply

    I would like to show some thanks to this writer just for rescuing me from this particular trouble. As a result of checking through the online world and meeting concepts which are not pleasant, I believed my life was over. Existing devoid of the solutions to the difficulties you’ve resolved all through this report is a serious case, as well as the kind which might have in a wrong way damaged my career if I had not noticed the blog. That natural talent and kindness in maneuvering a lot of stuff was precious. I’m not sure what I would have done if I had not discovered such a stuff like this. I can also at this moment look ahead to my future. Thank you very much for this high quality and effective guide. I won’t hesitate to refer the sites to anybody who should get care about this subject matter.

  19. November 20, 2021 at 7:08 am - Reply

    You made a number of good points there. I did a search on the subject matter and found most folks will have the same opinion with your blog.

  20. Www aainflight com November 20, 2021 at 10:07 am - Reply

    We stumbled over here different web page and thought I might check things out. I like what I see so now i am following you. Look forward to exploring your web page again.

  21. jet blue mastercard November 21, 2021 at 11:31 am - Reply

    Very nice post. I just stumbled upon your weblog and wished to say that I’ve truly enjoyed browsing your blog posts. In any case Ill be subscribing to your rss feed and I hope you write again very soon!

  22. November 22, 2021 at 3:34 pm - Reply

    I know this if off topic but I’m looking into starting my own blog and was wondering what all is required to get set up? I’m assuming having a blog like yours would cost a pretty penny? I’m not very web savvy so I’m not 100 sure. Any suggestions or advice would be greatly appreciated. Cheers

  23. Click here November 23, 2021 at 1:27 am - Reply

    My spouse and I stumbled over here different page and thought I might as well check things out. I like what I see so now i’m following you. Look forward to looking at your web page repeatedly.

  24. Paramountnetwork activate November 23, 2021 at 1:32 am - Reply

    Thank you so much for providing individuals with an exceptionally brilliant opportunity to read critical reviews from this web site. It is often very enjoyable and also packed with amusement for me and my office acquaintances to search the blog particularly thrice weekly to study the fresh things you have. And definitely, I’m so certainly happy concerning the effective thoughts served by you. Certain 1 ideas on this page are easily the most efficient we have had.

  25. Best Dating Site November 23, 2021 at 5:31 am - Reply


  26. activate November 23, 2021 at 8:58 pm - Reply

    Hello! Someone in my Facebook group shared this website with us so I came to give it a look. I’m definitely enjoying the information. I’m bookmarking and will be tweeting this to my followers! Terrific blog and fantastic design.

  27. Bessie Henrity November 25, 2021 at 4:32 pm - Reply

    Tolorosa href [url=] -tlm urll [/url] -ca4c

  28. Ollo mastercard review November 25, 2021 at 9:28 pm - Reply

    Hmm it appears like your blog ate my first comment (it was super long) so I guess I’ll just sum it up what I wrote and say, I’m thoroughly enjoying your blog. I too am an aspiring blog writer but I’m still new to the whole thing. Do you have any suggestions for inexperienced blog writers? I’d really appreciate it.

  29. Muama enence instant translator November 26, 2021 at 12:49 am - Reply

    Im not that much of a online reader to be honest but your sites really nice, keep it up! I’ll go ahead and bookmark your website to come back down the road. All the best

  30. Muama instant translator November 26, 2021 at 4:46 am - Reply

    Very efficiently written post. It will be helpful to everyone who usess it, as well as yours truly :). Keep doing what you are doing – for sure i will check out more posts.

  31. Slabway foot massager price November 26, 2021 at 5:44 am - Reply

    My spouse and I stumbled over here coming from a different website and thought I might as well check things out. I like what I see so now i am following you. Look forward to finding out about your web page again.

  32. November 27, 2021 at 1:37 am - Reply

    Today, I went to the beach with my children. I found a sea shell and gave it to my 4 year old daughter and said “You can hear the ocean if you put this to your ear.” She placed the shell to her ear and screamed. There was a hermit crab inside and it pinched her ear. She never wants to go back! LoL I know this is totally off topic but I had to tell someone!

  33. Bluebird November 27, 2021 at 3:25 am - Reply

    Hello this is kinda of off topic but I was wanting to know if blogs use WYSIWYG editors or if you have to manually code with HTML. I’m starting a blog soon but have no coding expertise so I wanted to get advice from someone with experience. Any help would be enormously appreciated!

  34. Anker powerhouse II 400 review November 27, 2021 at 7:03 pm - Reply

    Super-Duper website! I am loving it!! Will come back again. I am bookmarking your feeds also.

  35. Anker powerhouse 400 ii November 27, 2021 at 7:04 pm - Reply

    Hi there! Would you mind if I share your blog with my zynga group? There’s a lot of folks that I think would really appreciate your content. Please let me know. Cheers

  36. You may think pop quenches your thirst, but it will only leave you wanting more because of the sugar and caffeine.

  37. Best Dating App 2021 November 30, 2021 at 1:35 am - Reply

    ❤️ Alice want to meet you! Click Here: ❤️

  38. แทงบอล November 30, 2021 at 9:58 am - Reply

    Walk the field to make sure that there are no items that can cause players to trip and fall.

  39. December 1, 2021 at 12:07 am - Reply

    Howdy just wanted to give you a quick heads up. The words in your article seem to be running off the screen in Ie. I’m not sure if this is a formatting issue or something to do with internet browser compatibility but I thought I’d post to let you know. The style and design look great though! Hope you get the issue fixed soon. Thanks

  40. shortening to butter conversion December 1, 2021 at 3:13 am - Reply

    Wow, superb blog structure! How lengthy have you ever been running a blog for? you make running a blog glance easy. The entire look of your web site is wonderful, let alone the content material!

  41. Skywest employee login December 1, 2021 at 8:14 pm - Reply

    Wonderful goods from you, man. I have understand your stuff previous to and you’re just extremely excellent. I really like what you’ve acquired here, really like what you are stating and the way in which you say it. You make it enjoyable and you still take care of to keep it smart. I can’t wait to read far more from you. This is really a terrific web site.

  42. December 2, 2021 at 3:33 am - Reply

    I am really loving the theme/design of your website. Do you ever run into any browser compatibility problems? A handful of my blog visitors have complained about my website not operating correctly in Explorer but looks great in Chrome. Do you have any advice to help fix this issue?

  43. Skywestonline login December 2, 2021 at 8:54 am - Reply

    Hi there, You have done a fantastic job. I will definitely digg it and personally recommend to my friends. I am sure they will be benefited from this site.

  44. Paramountnetwork December 2, 2021 at 10:56 pm - Reply

    Hi, i think that i saw you visited my weblog thus i came to return the favor.I am trying to find things to enhance my site!I suppose its ok to use some of your ideas!!

  45. Disney plus begin December 3, 2021 at 12:56 am - Reply

    Hey there! Someone in my Facebook group shared this website with us so I came to give it a look. I’m definitely loving the information. I’m bookmarking and will be tweeting this to my followers! Superb blog and superb design.

  46. Paramountnetwork activate December 3, 2021 at 4:17 am - Reply

    Hi, i read your blog occasionally and i own a similar one and i was just curious if you get a lot of spam responses? If so how do you prevent it, any plugin or anything you can suggest? I get so much lately it’s driving me crazy so any support is very much appreciated.

  47. Bluebird card activation December 4, 2021 at 1:09 pm - Reply

    Its exhausting to search out knowledgeable people on this matter, however you sound like you know what youre speaking about! Thanks

  48. Bluebird activate new card December 4, 2021 at 8:03 pm - Reply

    Its actually a nice and helpful piece of info. Im glad that you shared this useful information with us. Please keep us up to date like this. Thanks for sharing.

  49. December 5, 2021 at 12:21 pm - Reply

    F*ckin tremendous things here. Im very glad to see your article. Thanks a lot and i am looking forward to contact you. Will you please drop me a mail?

  50. invitation number December 5, 2021 at 1:29 pm - Reply

    hey there and thank you for your info Ive certainly picked up something new from right here. I did however expertise some technical points using this website, as I experienced to reload the site many times previous to I could get it to load correctly. I had been wondering if your hosting is OK? Not that I’m complaining, but sluggish loading instances times will often affect your placement in google and could damage your high-quality score if ads and marketing with Adwords. Anyway I am adding this RSS to my e-mail and can look out for a lot more of your respective fascinating content. Make sure you update this again soon..

Leave A Comment

Join 10,000 Subscribers

Your information will never be shared
Sign up and receive the latest blog posts & take back your health!